ACNE

    Acne is an inflammatory condition of hair follicles that is prompted by occlusion (clogging) of pores.  Treatments are thus directed at opening the pores and controlling the inflammation.  Acne is stimulated at puberty when increased oil production occurs under hormonal influence (particularly androgens such as testosterone).  Oil leads to occlusion and is a source of nutrients for bacteria that live on the skin.  When the bacteria feed on the oil they break it down into factors that cause inflammatory cells to migrate into the follicle.  Understanding these processes will help you understand the basics of acne treatment. 

    Treatments for follicular occlusion (clogged pores).  Follicular occlusion leads to whiteheads and blackheads.  Factors affecting this include oil production and a build up of dead skin cells around the opening of the follicle (the pore).  Treatments include keratolytics that break up these dead skin cells such as the common over-the-counter treatments benzoyl peroxide, salicylic acid, and glycolyic acid.  Treatments that break up oil include various cleansers.  The gold standard for treating follicular occlusion are the Vitamin A-derived topicals called retinoids.  Retinoids both decrease oil production and decrease the stickiness of dead skin cells around the pore.  Retinoids can be either over-the-counter topicals such as adapalene 0.1% or prescription topicals such as higher strength adapalene, tretinoin or tazarotene.

    Treatments for inflammation.  Anti-inflammatory strategies include antibiotics to decrease bacterial presence on the skin as well as products that work directly to inhibit inflammatory pathways.  Antibiotic therapies include many topicals such as the facial cleansers as well as benzoyl peroxide; prescription topical antibiotics include clindamycin, erythromycin, and azelaic acid.  Products that inhibit inflammation directly include the prescription topical dapsone.  When inflammation is severe, oral antibiotics are often considered.  The most common class of oral antibiotics is the tetracycline family which includes doxycycline and minocycline; tetracyclines are both anti-bacterial and have an ability to inhibit inflammatory pathways directly.

    Severe cases of acne: In cases in which the standard therapies have failed to control the severest form of acne (nodulocystic), isotretinoin, an oral retinoid commonly known by its previous brand name Accutane, can be considered.  Because of the many potential side effects of this medication, this drug should only be prescribed by the professionals in a dermatology office.

    Other strategies:

    spironolactone and certain oral contraceptives (OCPs) for women:  these reduce levels of pro-acne testosterone; these agents are particularly helpful for women who have acne in the beard area and who have pre-menstrual flares

    photodynamic therapy (PDT) (Blu-U): PDT can decrease oil production in the skin and appears to kill bacteria as well; it is used for moderate to severe acne

    As always, you can contact our office to answer any questions or concerns.

    Search Results
    Niagara Dermatology Associates
    ...This field deals with not only the medical conditions that affect the skin (like psoriasis, rashes, acne, skin infections and skin cancer), but we are skin surgeons dealing with both benign and malignant conditions of the skin (such as the treatment of cysts, moles or nevi and skin cancers like melanoma),as well as cosmetic dermatology or the cosmetic enhancement of the skin...

    Patient Education
    ACNE Acne is an inflammatory condition of hair follicles that is prompted by occlusion (clogging) of pores...

    Our Services
    ... Acne Age Spot Removal Facials/HydraFacial Laser Hair Removal Moles (Nevi) Psoriasis Rashes Rosacea Pediatric Dermatology Skin Cancers Warts BLU-U MOHS   Acne Acne is the most frequent skin condition seen by medical professionals...

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    ...  Acne Treatment The BLU-U Blue Light Photodynamic Therapy Illuminator is also FDA cleared to treat moderate inflammatory acne vulgaris...

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    ... The BLU-U®  Blue Light Photodynamic Therapy Illuminator is also FDA cleared to treat moderate inflammatory acne vulgaris...

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    ... Read IPL Photofractional™ The Lumenis® Photofractional™ treatment is a complete skin rejuvenation solution, enabling your physician to offer you remarkable results on a range of skin aging concerns such as age and sun apots, fine lines, acne scars, uneven texture and skin tone...

    IPL Photo Rejuvenation
    ... The Lumenis® Photofractional™ solution The Lumenis® Photofractional™ treatment is a complete skin rejuvenation solution, enabling your physician to offer you remarkable results on a range of skin aging concerns such as age and sun apots, fine lines, acne scars, uneven texture and skin tone...

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    ... Rough, scaly patches that are sometimes itchy White or red bumps that look like acne Bumps on the arms, legs, cheeks or butt An increase in symptoms during the winter If you’ve said “yes” to any of these symptoms above, then your bumps may be the result of keratosis pilaris...

    Dermal Fillers and Wrinkles
    ...They were designed to treat acne, but when studies using these products in the treatment of adult female acne showed improvements in wrinkles and photoaging, they showed a new niche in antiaging...

    Pediatric Dermatology
    ... That's because when children go through puberty, they have such a dramatic rise in hormones that it can trigger a large number of dermatologist problems, including acne, pimples, redness, and oily skin...

    Age Spot Removal
    ... Read IPL Photofractional™ The Lumenis® Photofractional™ treatment is a complete skin rejuvenation solution, enabling your physician to offer you remarkable results on a range of skin aging concerns such as age and sun apots, fine lines, acne scars, uneven texture and skin tone...

    Facials - HydraFacial
    ...   The bonus of having the HydraFacial completed in the doctor’s office is that we can offer additional products as an adjunct to the procedure and other products to go along with the facial that can only be obtained from a physician, achieving greater results for specific concerns such as antiaging, rosacea and acne...

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    ... Sun exposure, acne, genetics and hormonal changes can trigger or worsen irregular pigmentation...

    Are You Dealing With Acne?
    Discover helpful acne-fighting tips and trick to achieve clearer skin...

    acne
    Acne is an inflammatory condition of hair follicles that is prompted by occlusion (clogging) of pores...

    rosacea
    ...  It is often referred to as adult acne becasue of its similarity of having inflamed follicle-based lesions that can sometimes become pustular like acne but unlike acne, rosacea does not have blackheads...

    acne treatment
    ACNE Acne is an inflammatory condition of hair follicles that is prompted by occlusion (clogging) of pores...

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